Suddenly, TwinCAT 3.1.4022.16 have got an error of compatibility with the latest update of Windows 10 version 1803. Local runtime of TwinCAT x64 drops down with exception after an attempt to switch into the run mode.
This error occurs both in Home and in Pro versions of Windows 10. The engineering version of the TwinCAT tools still work properly. We are waiting for a new update of TwinCAT.